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当前位置:3分pk10 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Mouse

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  • Procell-LR3-IGF1 (C-6His), Mouse, Recombinant

LR3-IGF1 (C-6His), Mouse, Recombinant

货号:PCK018

价格:¥500¥780¥5880¥8280

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 IGF1; IGF-1; Insulin-Like Growth Factor 1; Insulin-Like Growth Factor I; Somatomedin C; somatomedin-C
物种 Mouse
表达宿主 E.coli
序列信息 Gly49-Ala118
检索号 P05017
分子量 10.2 kDa
表观分子量 12 kDa

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,1mM EDTA,pH8.0.
复融 Please refer to it for detailed information.

背景介绍

Insulin-Like Growth Factor I (IGF1) belongs to the family of Insulin-Like Growth Factors that are structurally homologous to proInsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the Insulin Receptor. IGF-I association with IGF binding Proteins increases its plasma half-life and modulates its interactions with Receptors.